Growth hormone safe for infants with chronic renal failure

June 4, 2010

Growth hormone may be a safe and effective treatment to promote growth, without adverse effects, in infants with chronic renal failure, good nutrition, and adequate metabolic and clinical care, ...

Off-label use of recombinant IGF-I for growth promotion: Is it warranted?

April 1, 2010

Promotion of off-label use of recombinant human insulin-like growth factor I began as soon as FDA orphan drug approval was given late in 2005 for its use in growth hormone insensitivity due to g...

Treatment of short children with GH plus IGF-I: Are two hormones better than one?

December 1, 2009

Treatment with growth hormone is an established option for children with short stature due to a variety of causes. Approved indications include documented GH deficiency (GHD), Turner’s synd...

Body composition, ovarian function normal in women treated with Gn-RH analog during childhood

November 20, 2009

Women treated with gonadotropin-releasing hormone analog treatment during childhood had normal BMI, bone mineral density, body composition and ovarian function during early adulthood. In additio...

Individualized GH dosing promoted catch-up growth in children with GH deficiency, ISS

March 3, 2009

Prepubertal children with growth hormone deficiency or idiopathic short stature who received individualized growth hormone treatment during catch-up growth experienced equal growth responses to ...

Growth hormone therapy found safe and effective for children with ISS

November 20, 2008

Compared with untreated controls, growth hormone treatment increased final height in non–GH-deficient children with idiopathic short stature. Researchers from the Karolinska Institute and other sites...

Growth and Growth Hormone: Current Applications and Clinical Updates CME

October 25, 2008

Introduction Advances in the Diagnosis of Growth and Growth Hormone-Related Deficiencies Ron G. Rosenfeld, MD Metabolic Consequences of Growth-Hormone Deficiency Mark A. Sperling, MD D...

Adult height prediction model useful in children born small for gestational age

February 22, 2008

In short children born small for gestational age treated with growth hormone, the prediction model for adult height provides valuable knowledge of probable long-term growth. Researchers from The Neth...

Growth hormone slightly improved height increase

October 1, 2007

Children and adolescents with idiopathic short stature showed increased short-term growth and improved near final height when treated with growth hormone; however, additional research is necessary. ...

IGF-I–based GH dosing improved growth responses, required higher GH dose

August 1, 2007

Growth hormone dosing based on insulin-like growth factor I levels rather than weight led to an improved growth response, according to a study published in The Journal of Clinical Endocrinology and Me...